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. 1976 May;11(5):408-11.
doi: 10.1007/BF02532848.

Glycodihydrofusidate: biliary excretion and its effect on biliary secretion of the rat

J C Montet, A M Montet, A Gerolami, J Amic, J C Hauton

Glycodihydrofusidate: biliary excretion and its effect on biliary secretion of the rat

J C Montet et al. Lipids. 1976 May.

Abstract

Glycodihydrofusidate, which has the same detergent properties a bile salts, is excreted almost exclusively by the bile duct after intravenous injection in the rat. As with bile salts, it leads to a significant (P less tthan or equal to 0.05) increase in excretion of lecithins and cholesterol (0.15 mumol lecithin and 0.026 mumol cholesterol per 1 mumol of glycodihydrofusidate excreted). In addition, this drug simulataneously inhibits excretion of both endogenous bile salts and bile pigments.

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