Review
doi: 10.1016/s1535-6108(03)00081-3.
p53 mutations and resistance to chemotherapy: A stab in the back for p73
Affiliations
- PMID: 12726854
- DOI: 10.1016/s1535-6108(03)00081-3
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Review
p53 mutations and resistance to chemotherapy: A stab in the back for p73
Cancer Cell.
2003 Apr.
Free article
Abstract
p73 is essential for apoptosis induced by many cytotoxic agents, but this function can be blocked by a particular category of p53 mutations that have consequently acquired a gain of function.
Comment on
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p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis.Cancer Cell. 2003 Apr;3(4):387-402. doi: 10.1016/s1535-6108(03)00079-5. Cancer Cell. 2003. PMID: 12726864
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Chemosensitivity linked to p73 function.Cancer Cell. 2003 Apr;3(4):403-10. doi: 10.1016/s1535-6108(03)00078-3. Cancer Cell. 2003. PMID: 12726865
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