Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003 May;41(5):2161-3.
doi: 10.1128/JCM.41.5.2161-2163.2003.

Usefulness of urinary antigen detection by an immunochromatographic test for diagnosis of pneumococcal pneumonia in children

J Domínguez  1 , S Blanco, C Rodrigo, M Azuara, N Galí, A Mainou, A Esteve, A Castellví, C Prat, L Matas, V Ausina
Affiliations

Usefulness of urinary antigen detection by an immunochromatographic test for diagnosis of pneumococcal pneumonia in children

J Domínguez et al. J Clin Microbiol. 2003 May.

Abstract

We evaluated an immunochromatographic assay detecting pneumococcal antigen in urine samples from children diagnosed with pneumococcal pneumonia. The sensitivity and specificity of the immunochromatographic test with nonconcentrated urine (NCU) were 86.7 and 62.9%, respectively; with concentrated urine (CU), they were 100 and 11.7%, respectively. Pneumococcal antigen was also detected in 42.5% of NCU and 87.1% of CU samples from nasopharyngeal carriers. This is a nonspecific test for the diagnosis of pneumococcal pneumonia in children, particularly the very young.

PubMed Disclaimer

References

    1. Adegbola, R. A., S. K. Obaro, E. Biney, and B. M. Greenwood. 2001. Evaluation of Binax Now Streptococcus pneumoniae urinary antigen test in children in a community with a high carriage rate of pneumococcus. Pediatr. Infect. Dis. J. 20:718-719. - PubMed
    1. Ausina, V., P. Coll, M. Sambeat, I. Puig, M. J. Condom, M. Luquin, F. Ballester, and G. Prats. 1988. Prospective study on the etiology of community acquired pneumonia in children and adults in Spain. Eur. J. Clin. Microbiol. Infect. Dis. 7:343-347. - PubMed
    1. Burel, E., P. Dufour, V. Gauduchon, S. Jarraud, and J. Etienne. 2001. Evaluation of a rapid immunochromatographic assay for detection of Streptococcus pneumoniae antigen in urine samples. Eur. J. Clin. Microbiol. Infect. Dis. 20:840-841. - PubMed
    1. Coonrod, J. D., and M. W. Rytel. 1973. Detection of type-specific pneumococcal antigens by counterimmunoelectrophoresis. 1. Methodology and immunologic properties of pneumococcal antigens. J. Lab. Clin. Med. 81:770-777. - PubMed
    1. Domínguez, J., N. Galí, S. Blanco, P. Pedroso, C. Prat, L. Matas, and V. Ausina. 2001. Detection of Streptococcus pneumoniae antigen by a rapid immunochromatographic assay in urine samples. Chest 119:243-249. - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources