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Case Reports
. 2003 May;18(5):465-7.
doi: 10.1007/s00467-002-0973-4. Epub 2003 Mar 28.

Peripheral gangrene complicating hemolytic uremic syndrome in a child

Ahmet Ozel  1 , Umran Calişkan, Safak Gücer
Affiliations
Case Reports

Peripheral gangrene complicating hemolytic uremic syndrome in a child

Ahmet Ozel et al. Pediatr Nephrol. 2003 May.

Abstract

A patient with hemolytic uremic syndrome (HUS) developed peripheral gangrene involving all fingers and toes. There was no history of bloody diarrhea. Hypocomplementemia was present, with a serum C3 concentration of 41 mg/dl. Acute renal failure was treated with peritoneal dialysis for 4 months. He received daily fresh-frozen plasma infusions and plasmapheresis on alternate days for ten sessions, followed by once-weekly sessions. He was anuric for 9 weeks. All medial and distal phalanxes became necrotic and were removed surgically. The renal biopsy findings were consistent with HUS. This is the second report of peripheral gangrene during the course of HUS in childhood.

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