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. 2003 May;10(3):443-5.
doi: 10.1128/cdli.10.3.443-445.2003.

Immunohematological reference ranges for adults from the Central African Republic

Didier Menard  1 , Marie Joelle Mandeng, Mesmin Bem Tothy, Eric Kassa Kelembho, Gérard Gresenguet, Antoine Talarmin
Affiliations

Immunohematological reference ranges for adults from the Central African Republic

Didier Menard et al. Clin Diagn Lab Immunol. 2003 May.

Abstract

A survey was carried out on 150 healthy adults to establish hematological reference ranges for human immunodeficiency virus (HIV)-negative adults from the Central African Republic (CAR). Immunohematological mean values, medians, and 95th-percentile reference ranges were established. Mean values were as follows: leukocyte (WBC) counts, 5.28 x 10(9)/liter (males) and 5.11 x 10(9)/liter (females); erythrocyte counts, 5.20 x 10(12)/liter (males) and 4.50 x 10(12)/liter (females); hemoglobin, 15.1 g/dl (males) and 12.5 g/dl (females); hematocrit, 45% (males) and 37% (females); lymphocytes, 2,587/ micro l (males) and 2,466/ micro l (females); CD4 T cells, 927/ micro l (males) and 940/ micro l (females); CD8 T cells, 898/ micro l (males) and 716/ micro l (females); and CD4/CD8 T-cell ratio, 1.13 (males) and 1.41 (females). We concluded that (i) the WBC and hemoglobin values of healthy HIV-negative adults from the CAR are lower than the reference values currently used in the CAR and (ii) the absolute CD4 T-cell counts of healthy HIV-negative adults from the CAR are similar to values for Europeans but the absolute CD8 T-cell counts are much higher. Thus, the CD4/CD8 T-cell ratios for healthy adults from the CAR are significantly reduced compared to the ratios for healthy Europeans.

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References

    1. Al Qouzi, A., A. Al Salamah, R. Al Rasheed, A. Al Musalam, K. Al Khairy, O. Kheir, S. Al Ajaji, and A. H. Hajeer. 2002. Immunophenotyping of peripheral blood lymphocytes in Saudi men. Clin. Diagn. Lab. Immunol. 9:279-281. - PMC - PubMed
    1. Badenhorst, C. J., J. Fourie, K. Steyn, P. L. Jooste, C. J. Lombard, L. Bourne, and W. Slazus. 1995. The haematological profile of urban black Africans aged 15-64 years in the Cape Peninsula. East Afr. Med. J. 72:19-24. - PubMed
    1. Chin, S. F., S. K. Cheoug, Y. C. Lim, and S. H. Ton. 1993. The distribution of immunoregulatory cells in the peripheral blood of normal Malaysian adults. Malays. J. Pathol. 15:49-52. - PubMed
    1. Choong, M. L., S. H. Yon, and S. K. Cheong. 1995. Influence of race, age and sex on the lymphocyte subsets in peripheral blood of healthy Malaysian adults. Ann. Clin. Biochem. 32:532-539. - PubMed
    1. Coetzee, M. J., P. N. Badenhorst, J. I. de Wit, and G. Joubert. 1994. Haematological condition of the San (Bushmen) relocated from Namibia to South Africa. S. Afr. Med. J. 84:416-420. - PubMed

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