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. 2003 Jun;29(6):870-875.
doi: 10.1007/s00134-003-1821-0. Epub 2003 May 9.

ICU management of severe acute respiratory syndrome

Affiliations

ICU management of severe acute respiratory syndrome

Stephen E Lapinsky et al. Intensive Care Med. 2003 Jun.

Abstract

Background: Severe acute respiratory syndrome (SARS) is a contagious viral illness first recognized in late 2002. It has now been documented in 26 countries worldwide, with significant outbreaks in China, Hong Kong, Singapore, and Toronto. Research into identifying the etiological agent, evaluating modes of disease transmission, and treatment options is currently ongoing.

Discussion: The disease can produce a severe bilateral pneumonia, with progressive hypoxemia. Up to 20% of patients require mechanical ventilatory support, with a fatal outcome occurring in about 5% of cases.

Conclusions: We review the current knowledge about this disease, with particular emphasis on ICU management and infection control precautions to prevent disease transmission.

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References

    1. Ksiazek TG, Erdman D, Goldsmith CS, Zaki SR, Peret T, Emery S, Tong S, Urbani C, Comer JA, Lim W, Rollin PE, Dowell SF, Ling AE, Humphrey CD, Shieh WJ, Guarner J, Paddock CD, Rota P, Fields B, DeRisi J, Yang JY, Cox N, Hughes JM, LeDuc JW, Bellini WJ, Anderson LJ (2003) A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med, 10 April (on-line publication ahead of print) - PubMed
    1. Drosten C, Gunther S, Preiser W, Van Der Werf S, Brodt HR, Becker S, Rabenau H, Panning M, Kolesnikova L, Fouchier RA, Berger A, Burguiere AM, Cinatl J, Eickmann M, Escriou N, Grywna K, Kramme S, Manuguerra JC, Muller S, Rickerts V, Sturmer M, Vieth S, Klenk HD, Osterhaus AD, Schmitz H, Doerr HW (2003) Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med, 10 April (on-line publication ahead of print) - PubMed
    1. Anonymous MMWR Morb Mortal Wkly Rep. 2003;52:255. - PubMed
    1. Tsang KW, Ho PL, Ooi GC, Yee WK, Wang T, Chan-Yeung M, Lam WK, Seto WH, Yam LY, Cheung TM, Wong PC, Lam B, Ip MS, Chan J, Yuen KY, Lai KN (2003) A cluster of cases of severe acute respiratory syndrome in Hong Kong. N Engl J Med, 31 March (on-line publication ahead of print) - PubMed
    1. Poutanen SM, Low DE, Henry B, Finkelstein S, Rose D, Green K, Tellier R, Draker R, Adachi D, Ayers M, Chan AK, Skowronski DM, Salit I, Simor AE, Slutsky AS, Doyle PW, Krajden M, Petric M, Brunham RC, McGeer AJ (2003) Identification of severe acute respiratory syndrome in Canada. N Engl J Med, 31 March (on-line publication ahead of print) - PubMed

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