Does the consumption of amylase-containing gruels impact on the energy intake and growth of Congolese infants?

Abstract

Objective: To assess the effect of the incorporation of amylase in maize-based flours prepared as gruels on the energy intake and growth of Congolese infants.

Design: A randomised controlled trial. At 18 weeks of age, infants were randomised into either an intervention group, where they were provided with a maize/soya-based flour that contained amylase, or a control group, where they were provided with a similar flour that did not contain amylase.

Setting: Urban borough of Poto-Poto in Brazzaville, The Congo.

Subjects: Eighty infants (40 in each group) were randomised into intervention and control groups. Three infants in the intervention group and two controls subsequently dropped out.

Results: At 24 weeks, the addition of amylase resulted in a significant increase in energy intake (in kJ kg-1 day-1) from gruels without affecting breast milk consumption. In contrast, total energy intake (in kJ kg-1 day-1) did not differ significantly between groups (P= 0.08). After adjustment for morbidity and previous growth, infants in the intervention group showed better growth in length during the trial (+0.22 cm month-1; P= 0.04), especially between 24 and 31 weeks of age (+0.51 cm month-1; P< 0.01). There were no differences in weight velocity between groups.

Conclusions: The findings of this study suggest that the consumption of amylase-treated gruels allows an increase in energy intake from these gruels without affecting breast milk consumption but has no impact on total daily energy intake. However, if started after 6 months, it could be effective in preventing faltering of infant linear growth.