A case of juvenile systemic sclerosis with disease onset at six months old

Abstract

Systemic sclerosis (SSc) is a generalised connective tissue disorder characterised by sclerotic changes in the skin and internal organs. The occurrence of SSc in childhood is rare, with childhood-onset disease representing 3% of all SSc cases, and fewer than 100 such patients have been reported in the world literature to date [1]. We report a case of juvenile SSc with disease onset at the age of 6 months. To our knowledge, this case is the youngest in the world literature.