[Stromal stem cells and osteoblastic cellular differon]

Abstract

The article presents an analysis of the data on the origin, differentiation, morpho-functional characteristics and reactivity of the bone cells taking into account theoretical concepts of histogenetic series and cell differons. The information on the sources and proliferation of cells of the osteogenic line was used as the basis for development of a variant of a scheme describing the differentiation of these cells from a stromal stem cell (SSC) to a bone-lining cell and osteocyte. Considering possible differentiation of SSC into the cells of fibroblastic, chondroblastic, adipocytic and leiomyocytic cell lines, the unified model of mechonocytogenesis is proposed.