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Review
. 2003 May 8;38(3):362-5.
doi: 10.1016/s0896-6273(03)00262-9.

Excitement reduces inhibition via endocannabinoids

Tamás F Freund  1 , Norbert Hájos
Affiliations
Free article
Review

Excitement reduces inhibition via endocannabinoids

Tamás F Freund et al. Neuron. .
Free article

Abstract

Previous work has suggested a role for retrograde synaptic signaling via endogenous cannabinoids in regulating the inhibitory control of neuronal activity. In this issue of Neuron, Chevaleyre and Castillo provide evidence for another form of endocannabinoid-mediated depression of hippocampal inhibition, which is activity dependent and long lasting.

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