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. 2003 May;188(5):1297-8.
doi: 10.1067/mob.2003.346.

Treatment of nonatypical and atypical endometrial hyperplasia with a levonorgestrel-releasing intrauterine system

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Treatment of nonatypical and atypical endometrial hyperplasia with a levonorgestrel-releasing intrauterine system

D Wildemeersch et al. Am J Obstet Gynecol. 2003 May.

Abstract

Objective: A "frameless" intrauterine drug delivery system that releases 14 microg/d of levonorgestrel was used to treat nonatypical and atypical endometrial hyperplasia in 12 women.

Study design: This noncomparative study had up to 3 to 4 years of follow-up.

Results: The cure rate was 100%, as confirmed by repeat endometrial biopsy.

Conclusion: This method could be considered an alternative to hysterectomy.

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