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. 1976 Feb;21(2):81-8.
doi: 10.1007/BF01072046.

Crohn's disease of the colon. Analysis of the diagnostic value of radiology, endoscopy, and histology

S G Meuwissen, K S Pape, D Agenant, H H Oushoorn, G N Tytgat

Crohn's disease of the colon. Analysis of the diagnostic value of radiology, endoscopy, and histology

S G Meuwissen et al. Am J Dig Dis. 1976 Feb.

Abstract

Radiologic, endoscopic, and histologic features were analyzed in 15 patients with Crohn's disease of the colon. Radiologic findings were considered of diagnostic value in only 6 (40%), characteristic endoscopic lesions were found in 13 (87%) and diagnostic histologic features in 11 (73%). Endoscopy combined with biopsy was diagnostic in all 15 cases. The extent of involvement of endoscopy frequently disagreed with the radiologic assessment, particularly in the rectosigmoid area. Studies in 8 patients indicate that sigmoidoscopy and coloscopy with multiple biopsies provide an accurate alternative to radiology to estimate the extent and severity of the lesions and their evolution during corticosteroid and/or azathioprine treatment.

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