Review
doi: 10.1023/a:1023025506386.
Profiling breast cancer by array CGH
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- PMID: 12755488
- DOI: 10.1023/a:1023025506386
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Review
Profiling breast cancer by array CGH
Breast Cancer Res Treat.
2003 Apr.
Free article
Abstract
Breast tumors display a wide variety of genomic alterations. This review focuses on DNA copy number variations in these tumors as measured by the recently developed microarray-based form of comparative genomic hybridization. The capabilities of this new technology are reviewed. Initial applications of array CGH to the analysis of breast cancer, and the mechanisms by which the particular types of copy number changes might arise are discussed.
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