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Review
. 2003 Apr;78(3):289-98.
doi: 10.1023/a:1023025506386.

Profiling breast cancer by array CGH

Donna G Albertson  1
Affiliations
Free article
Review

Profiling breast cancer by array CGH

Donna G Albertson. Breast Cancer Res Treat. 2003 Apr.
Free article

Abstract

Breast tumors display a wide variety of genomic alterations. This review focuses on DNA copy number variations in these tumors as measured by the recently developed microarray-based form of comparative genomic hybridization. The capabilities of this new technology are reviewed. Initial applications of array CGH to the analysis of breast cancer, and the mechanisms by which the particular types of copy number changes might arise are discussed.

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