Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003 May 16;113(4):422-3.
doi: 10.1016/s0092-8674(03)00358-1.

Fusion with the fused: a new role for interleukin-4 in the building of muscle

Sophie Chargé  1 , Michael A Rudnicki
Affiliations
Free article
Review

Fusion with the fused: a new role for interleukin-4 in the building of muscle

Sophie Chargé et al. Cell. .
Free article

Abstract

In this issue of Cell, G. Pavlath and coworkers demonstrate a novel role for Interleukin-4 (IL-4) in regulating the fusion of myoblasts with differentiated myotubes. The authors demonstrate that NFATc2 signaling in newly formed myotubes induces IL-4 expression and secretion which promotes myoblast fusion with pre-existing myotubes.

PubMed Disclaimer

Comment on

MeSH terms

LinkOut - more resources