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. 1976 Feb 1;153(2):509-12.
doi: 10.1042/bj1530509.

Artifacts in the centrifugation of ribosomal and heterogenous ribonucleic acid in "99%-dimethyl sulphoxide" gradients

Artifacts in the centrifugation of ribosomal and heterogenous ribonucleic acid in "99%-dimethyl sulphoxide" gradients

I H Maxwell. Biochem J. .

Abstract

Increasing the total quantity of RNA located on 99%-dimethyl sulphoxide gradients profoundly altered the sedimentation pattern of heterogenous RNA and (to a smaller extent) that of rRNA. Aggregation of small quantities of rRNA with fast-sedimenting heterogenous RNA was also found to occur in these gradients.

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