Porcine malignant hyperthermia. II: Heat production
- PMID: 1275997
- DOI: 10.1093/bja/48.4.305
Porcine malignant hyperthermia. II: Heat production
Abstract
The contributions of aerobic and anaerobic muscle metabolism to the heat produced in porcine malignant hyperthermia were studied in seven Pietrain pigs. Oxygen consumption measurements were used to calculate the increase in muscle temperature as a result of aerobic metabolism and this was compared with the observed muscle temperature. The results show that in the initial stage of porcine malignant hyperthermia heat production is largely aerobic in origin. Terminally, aerobic metabolism can account for about half the observed temperature increase.
Similar articles
-
Porcine malignant hyperthermia: role of skeletal muscle in increased oxygen consumption.Can Anaesth Soc J. 1977 Jan;24(1):103-9. doi: 10.1007/BF03006817. Can Anaesth Soc J. 1977. PMID: 832173
-
Porcine malignant hyperthermia. I: Metabolic and physiological changes.Br J Anaesth. 1976 Apr;48(4):297-304. doi: 10.1093/bja/48.4.297. Br J Anaesth. 1976. PMID: 1275996
-
Suxamethonium-induced porcine malignant hyperthermia.Br J Anaesth. 1976 Jun;48(6):513-7. doi: 10.1093/bja/48.6.513. Br J Anaesth. 1976. PMID: 952685
-
Anaesthesia of pigs sensitive to malignant hyperthermia.Vet Rec. 1977 Jan 15;100(3):45-8. doi: 10.1136/vr.100.3.45. Vet Rec. 1977. PMID: 319590 Review.
-
Treatment of porcine malignant hyperthermia. A review based on experimental studies.Anaesthesia. 1975 May;30(3):308-17. doi: 10.1111/j.1365-2044.1975.tb00861.x. Anaesthesia. 1975. PMID: 238411 Review.
Cited by
-
Etiopathogenetic defect of malignant hyperthermia: hypersensitive calcium-release channel of skeletal muscle sarcoplasmic reticulum.Vet Res Commun. 1987;11(6):527-59. doi: 10.1007/BF00396370. Vet Res Commun. 1987. PMID: 2453969 Review. No abstract available.
-
Thermogenesis in stress-susceptible pigs: a review.J R Soc Med. 1983 Jun;76(6):514-7. doi: 10.1177/014107688307600613. J R Soc Med. 1983. PMID: 6864722 Free PMC article. No abstract available.
-
From Mice to Humans: An Overview of the Potentials and Limitations of Current Transgenic Mouse Models of Major Muscular Dystrophies and Congenital Myopathies.Int J Mol Sci. 2020 Nov 25;21(23):8935. doi: 10.3390/ijms21238935. Int J Mol Sci. 2020. PMID: 33255644 Free PMC article. Review.
-
Porcine malignant hyperthermia: role of skeletal muscle in increased oxygen consumption.Can Anaesth Soc J. 1977 Jan;24(1):103-9. doi: 10.1007/BF03006817. Can Anaesth Soc J. 1977. PMID: 832173
-
Malignant hyperthermia: molecular defects in membrane permeability.Experientia. 1985 May 15;41(5):656-61. doi: 10.1007/BF02007707. Experientia. 1985. PMID: 3888661 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources