This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Review

. 2000:65:443-9.

doi: 10.1101/sqb.2000.65.443.

Establishment of and recovery from damage checkpoint requires sequential interactions of Crb2 with protein kinases Rad3, Chk1, and Cdc2

F Esashi¹, S Mochida, T Matsusaka, T Obara, A Ogawa, K Tamai, M Yanagida

Affiliations

Affiliation

¹ CREST Research Project, Department of Gene Mechanisms, Graduate School of Biostudies, Kyoto University, Kitashirakawa-Oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan.

PMID: 12760060
DOI: 10.1101/sqb.2000.65.443

Review

Establishment of and recovery from damage checkpoint requires sequential interactions of Crb2 with protein kinases Rad3, Chk1, and Cdc2

F Esashi et al. Cold Spring Harb Symp Quant Biol. 2000.

. 2000:65:443-9.

doi: 10.1101/sqb.2000.65.443.

Authors

F Esashi¹, S Mochida, T Matsusaka, T Obara, A Ogawa, K Tamai, M Yanagida

Affiliation

¹ CREST Research Project, Department of Gene Mechanisms, Graduate School of Biostudies, Kyoto University, Kitashirakawa-Oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan.

PMID: 12760060
DOI: 10.1101/sqb.2000.65.443

No abstract available

PubMed Disclaimer

Similar articles

Regulation of checkpoint kinases through dynamic interaction with Crb2.
Mochida S, Esashi F, Aono N, Tamai K, O'Connell MJ, Yanagida M. Mochida S, et al. EMBO J. 2004 Jan 28;23(2):418-28. doi: 10.1038/sj.emboj.7600018. Epub 2004 Jan 22. EMBO J. 2004. PMID: 14739927 Free PMC article.
Hyperactive Cdc2 kinase interferes with the response to broken replication forks by trapping S.pombe Crb2 in its mitotic T215 phosphorylated state.
Mahyous Saeyd SA, Ewert-Krzemieniewska K, Liu B, Caspari T. Mahyous Saeyd SA, et al. Nucleic Acids Res. 2014 Jul;42(12):7734-47. doi: 10.1093/nar/gku452. Epub 2014 May 26. Nucleic Acids Res. 2014. PMID: 24861625 Free PMC article.
Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.
Saka Y, Esashi F, Matsusaka T, Mochida S, Yanagida M. Saka Y, et al. Genes Dev. 1997 Dec 15;11(24):3387-400. doi: 10.1101/gad.11.24.3387. Genes Dev. 1997. PMID: 9407031 Free PMC article.
Rad3 and Sty1 function in Schizosaccharomyces pombe: an integrated response to DNA damage and environmental stress?
Alao JP, Sunnerhagen P. Alao JP, et al. Mol Microbiol. 2008 Apr;68(2):246-54. doi: 10.1111/j.1365-2958.2008.06147.x. Mol Microbiol. 2008. PMID: 18366437 Review.
DNA damage: Chk1 and Cdc25, more than meets the eye.
Walworth NC. Walworth NC. Curr Opin Genet Dev. 2001 Feb;11(1):78-82. doi: 10.1016/s0959-437x(00)00160-x. Curr Opin Genet Dev. 2001. PMID: 11163155 Review.

See all similar articles

Cited by

Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1.
Abreu CM, Kumar R, Hamilton D, Dawdy AW, Creavin K, Eivers S, Finn K, Balsbaugh JL, O'Connor R, Kiely PA, Shabanowitz J, Hunt DF, Grenon M, Lowndes NF. Abreu CM, et al. PLoS Genet. 2013 Apr;9(4):e1003310. doi: 10.1371/journal.pgen.1003310. Epub 2013 Apr 4. PLoS Genet. 2013. PMID: 23593009 Free PMC article.
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks.
Du LL, Nakamura TM, Russell P. Du LL, et al. Genes Dev. 2006 Jun 15;20(12):1583-96. doi: 10.1101/gad.1422606. Genes Dev. 2006. PMID: 16778077 Free PMC article.
Regulation of checkpoint kinases through dynamic interaction with Crb2.
Mochida S, Esashi F, Aono N, Tamai K, O'Connell MJ, Yanagida M. Mochida S, et al. EMBO J. 2004 Jan 28;23(2):418-28. doi: 10.1038/sj.emboj.7600018. Epub 2004 Jan 22. EMBO J. 2004. PMID: 14739927 Free PMC article.

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Grants and funding

101009/Wellcome Trust/United Kingdom

LinkOut - more resources

Full Text Sources
- HighWire
Miscellaneous
- NCI CPTAC Assay Portal