Identification and quantitation of hypersensitivity reactions to intravenous anaesthetic agents
- PMID: 1276018
- DOI: 10.1093/bja/48.5.457
Identification and quantitation of hypersensitivity reactions to intravenous anaesthetic agents
Abstract
It is not possible to distinguish between direct pharmacological effects and immune-mediated hypersensitivity reactions by clinical observation alone and errors may occur in the absence of laboratory tests. A convenient and simple test is the measurement of plasma complement C3 consumption and conversion in sequential blood samples taken at intervals over the 24 h following an adverse response.
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