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Case Reports
. 2003 Mar;18(1):61-3.
doi: 10.3904/kjim.2003.18.1.61.

Very severe aplastic anemia appearing after thymectomy

Chi Young Park  1 , Hee Je Kim, Yoo Jin Kim, Yoon Hee Park, Jong Wook Lee, Woo Sung Min, Chun Choo Kim
Affiliations
Case Reports

Very severe aplastic anemia appearing after thymectomy

Chi Young Park et al. Korean J Intern Med. 2003 Mar.

Abstract

Aplastic anemia is a rare complication of thymoma and is extremely infrequent after thymectomy. We present a case of a 60-year-old woman with very severe aplastic anemia appearing sixteen months after thymectomy for a thymoma. She underwent thymectomy for a thymoma in April 2000. Preoperative examination revealed no hematologic abnormality. About sixteen months after the operation, she was readmitted because of pancytopenia with cough and fever. Bone marrow aspiration revealed a very severe hypoplasia in all the three cell lines with over 80% fatty tissue, and chest CT revealed no recurrence of thymoma. Her aplastic anemia had responded to cyclosporine A and granulocyte-colony stimulating factor (G-CSF).

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Figures

Figure 1.
Figure 1.
Chest computed tomography showed a large mass in the anterior mediastinum, compatible with a thymoma.
Figure 2.
Figure 2.
Clinical course of the patient with thymoma and aplastic anemia. CsA, cyclosporine A.
See this image and copyright information in PMC

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