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. 2003 Jun;47(6):2015-7.
doi: 10.1128/AAC.47.6.2015-2017.2003.

Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion

Baudouin Byl  1 , Frédérique Jacobs, Pierre Wallemacq, Camelia Rossi, Philippe de Francquen, Matteo Cappello, Teresinha Leal, Jean-Pierre Thys
Affiliations

Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion

Baudouin Byl et al. Antimicrob Agents Chemother. 2003 Jun.

Abstract

Blood and pleural exudate samples were obtained from 16 patients receiving intermittent or continuous infusions of vancomycin after lung surgery. The areas under the concentration-time curves for blood and pleural exudates were identical for both administration schedules, while continuous infusion allowed the concentrations in pleural exudates to be more sustained (mean concentration, 12 mg/liter).

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References

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