Cyclic nucleotide phosphodiesterase 5 and sildenafil: promises realized
- PMID: 12761329
- DOI: 10.1124/mol.63.6.1209
Cyclic nucleotide phosphodiesterase 5 and sildenafil: promises realized
Similar articles
-
Inhibition of type-5 phosphodiesterase: promising therapy for pulmonary hypertension.Intern Med. 2004 Oct;43(10):891-3. doi: 10.2169/internalmedicine.43.891. Intern Med. 2004. PMID: 15575233 No abstract available.
-
KF31327, a new potent and selective inhibitor of cyclic nucleotide phosphodiesterase 5.Eur J Pharmacol. 2001 Nov 9;431(1):17-24. doi: 10.1016/s0014-2999(01)01422-4. Eur J Pharmacol. 2001. PMID: 11716838
-
Cyclic GMP phosphodiesterase-5: target of sildenafil.J Biol Chem. 1999 May 14;274(20):13729-32. doi: 10.1074/jbc.274.20.13729. J Biol Chem. 1999. PMID: 10318772 Review. No abstract available.
-
Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds.Mol Pharmacol. 1999 Jul;56(1):124-30. doi: 10.1124/mol.56.1.124. Mol Pharmacol. 1999. PMID: 10385692
-
Phosphodiesterase 5 inhibitors and nitrergic transmission-from zaprinast to sildenafil.Eur J Pharmacol. 2001 Jan 5;411(1-2):1-10. doi: 10.1016/s0014-2999(00)00824-4. Eur J Pharmacol. 2001. PMID: 11137852 Review.
Cited by
-
Characterization of a catalytic ligand bridging metal ions in phosphodiesterases 4 and 5 by molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations.Biophys J. 2006 Sep 1;91(5):1858-67. doi: 10.1529/biophysj.106.086835. Biophys J. 2006. PMID: 16912214 Free PMC article.
-
Characterization of the structures of phosphodiesterase 10 binding with adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate by hybrid quantum mechanical/molecular mechanical calculations.J Phys Chem B. 2010 May 27;114(20):7022-8. doi: 10.1021/jp911527y. J Phys Chem B. 2010. PMID: 20443609 Free PMC article.
-
Efficacy and selectivity of phosphodiesterase-targeted drugs in inhibiting photoreceptor phosphodiesterase (PDE6) in retinal photoreceptors.Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3060-6. doi: 10.1167/iovs.05-0257. Invest Ophthalmol Vis Sci. 2005. PMID: 16123402 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources