Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003 May 15;23(10):3981-9.
doi: 10.1523/JNEUROSCI.23-10-03981.2003.

Neuroimaging weighs in: humans meet macaques in "primate" visual cortex

Roger B H Tootell  1 , Doris Tsao, Wim Vanduffel
Affiliations
Review

Neuroimaging weighs in: humans meet macaques in "primate" visual cortex

Roger B H Tootell et al. J Neurosci. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Maps of reported areas in primate visual cortex. Maps are shown on the flattened cortical surface from right hemisphere (light gray, gyri; dark gray, sulci). A shows areas in macaque reported by Van Essen and colleagues, and B shows the macaque areas reported by Ungerleider and collaborators (adapted from Van Essen et al., 2001). C shows areas in human visual cortex, as described in the text. Consensus is highest in lower-tier (generally, left-most) areas; such areas tend to be evolutionarily more conserved, and the retinotopy is more easily resolved.
Figure 2.
Figure 2.
Object-selective (LOc) activation in visual cortex of macaques and humans. In both species, fMRI (BOLD) data were acquired from awake subjects, who fixated the center of a common stimulus set. A shows those stimuli, presented in block design in an a–b–a–c sequence (a, 32 grid-scrambled objects; b, 32 different objects; c, one object, presented in two different views). B (macaque) and C (human) reveal regions activated more by objects than scrambled objects (red-orange) and the reverse (blue-cyan). D (macaque) and E (human) show corresponding fMRI levels in selected visual areas. The human region activated more by objects (C) has been named LOc; it corresponds primarily to higher-tier cortical areas TEO and TE in macaque (B). In both species, lower-tier retinotopic areas (e.g., V1, V2, V3) responded better to the control images (scrambled objects), making the reversal in higher-tier areas even more significant. In human LOc and macaque TEO/TE, there was a reduced response to presentations of the single object (condition c, dark gray) compared with the multiple objects (condition b, light gray). Thus macaque shows fMRI-based adaptation in inferotemporal cortex, similar to that in humans. Bold, Blood oxygen level dependent.
See this image and copyright information in PMC

References

    1. Aguirre GK, Singh R, D'Esposito M ( 1999) Stimulus inversion and the responses of face and object-sensitive cortical areas. NeuroReport 10: 189–194. - PubMed
    1. Allison T, Puce A, Spencer DD, McCarthy G ( 1999) Electrophysiological studies of human face perception. I: Potentials generated in occipitotemporal cortex by face and non-face stimuli. Cereb Cortex 9: 415–430. - PubMed
    1. Allman JM, Kaas JH, Lane RH ( 1973) The middle temporal visual area (MT) in the bushbaby, Galago senegalensis Brain Res 57: 197–202. - PubMed
    1. Backus BT, Fleet DJ, Parker AJ, Heeger DJ ( 2001) Human cortical activity correlates with stereoscopic depth perception. J Neurophysiol 86: 2054–2068. - PubMed
    1. Baker JF, Petersen SE, Newsome WT, Allman JM ( 1981) Visual response properties of neurons in four extrastriate visual areas of the owl monkey (Aotus trivirgatus): a quantitative comparison of medial, dorsomedial, dorsolateral, and middle temporal areas. J Neurophysiol 45: 397–416. - PubMed