Quality of life evidence in the management of the individual patient with atrial fibrillation

Abstract

It is remarkable that in patients with paroxysmal AF not sufficiently controlled by pharmacological therapy, ablation and pacemaker treatment is highly effective and superior to drug therapy in controlling symptoms and improving quality of life. The discontinuation of drug therapy exposes patients to further recurrences of paroxysmal AF and the risk of developing permanent AF. However, both pharmacological and electrical treatment can enhance quality of life in AF patients. Long-term survival after ablation of the atrioventricular node and implantation of a permanent pacemaker in patients with AF is similar for AF patients whether they receive ablation or drug therapy; i.e. control of the ventricular rate by ablation of the atrioventricular node and permanent pacing do not adversely affect long-term survival.