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Clinical Trial
. 1976 Jul 10;2(6027):73-4.
doi: 10.1136/bmj.2.6027.73.

High-dose corticosteroids in severe acute asthma

M G Britton, J V Collins, D Brown, N P Fairhurst, R G Lambert
Clinical Trial

High-dose corticosteroids in severe acute asthma

M G Britton et al. Br Med J. .

Abstract

Twenty-six patients admitted to hospital for treatment of severe exacerbations of asthma unresponsive to bronchodilators were assigned to high-, medium-, or low-dose corticosteroid treatment regimens. The rates of recovery were assessed by changes in pulse rate, peak expiratory flow rate, and spirometric measurements and were not related to the dose of corticosteroids given. Very high systemic doses of corticosteroids do not offer significant advantages in treating severe exacerbations of asthma.

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References

    1. Q J Med. 1975 Apr;44(174):259-73 - PubMed
    1. Lancet. 1970 Nov 21;2(7682):1047-9 - PubMed

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