Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003 Jun;268(2):105-6.
doi: 10.1007/s00404-002-0340-5. Epub 2002 Aug 17.

Etidronate and hormone replacement therapy (HRT) for postmenopausal women with osteoporosis despite HRT

Ken-ichirou Morishige  1 , Toshiya Yamamoto, Kenjiro Sawada, Masahide Ohmichi, Keiichi Tasaka, Yuji Murata
Affiliations

Etidronate and hormone replacement therapy (HRT) for postmenopausal women with osteoporosis despite HRT

Ken-ichirou Morishige et al. Arch Gynecol Obstet. 2003 Jun.

Abstract

Hormone replacement therapy (HRT) is effective treatment for postmenopausal bone loss and osteoporosis. However, postmenopausal women with low bone mass fail to respond after a few years of HRT and some postmenopausal women show no bone response to HRT. In these cases, additive therapy is necessary. Bisphosphonates are highly effective in postmenopausal osteoporosis. We investigated the effects of adding etidronate, a bisphosphonate, to HRT. The addition of etidronate to HRT improved bone density (4.40+/-1.12% increase per year) in patients showing no increase or even a decrease after at least 1 year of HRT (5.39+/-2.40% decrease per year).

PubMed Disclaimer

MeSH terms

LinkOut - more resources