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Clinical Trial
. 2003 May 6;88(9):1335-8.
doi: 10.1038/sj.bjc.6600914.

Phase II study of docetaxel in patients with relapsed or refractory malignant lymphoma

J M Zekri  1 , R E Hough, J M Davies, R Molife, B W Hancock, P C Lorigan
Affiliations
Clinical Trial

Phase II study of docetaxel in patients with relapsed or refractory malignant lymphoma

J M Zekri et al. Br J Cancer. .

Abstract

We report the activity and toxicity of docetaxel in 12 evaluable heavily pretreated patients with relapsed and refractory non-Hodgkin's lymphoma and Hodgkin's disease. In all, 42% achieved a partial response, 25% achieved stable disease. Median duration of response was 16 (10-21) weeks. The median overall survival was 70 (9-178) weeks and for responders it was 120 (22-178) weeks. One patient developed one episode of neutropenic sepsis. Docetaxel has limited activity in this group of patients.

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Figures

Figure 1
Figure 1
Overall survival (n=13).
Figure 2
Figure 2
Survival of diagnoses groups.
See this image and copyright information in PMC

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