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Review
. 2003 Jun;4(6):446-56.
doi: 10.1038/nrm1128.

Rocks: multifunctional kinases in cell behaviour

Kirsi Riento  1 , Anne J Ridley
Affiliations
Review

Rocks: multifunctional kinases in cell behaviour

Kirsi Riento et al. Nat Rev Mol Cell Biol. 2003 Jun.

Abstract

ROCKs, or Rho kinases, are serine/threonine kinases that are involved in many aspects of cell motility, from smooth-muscle contraction to cell migration and neurite outgrowth. Recent experiments have defined new functions of ROCKs in cells, including centrosome positioning and cell-size regulation, which might contribute to various physiological and pathological states.

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