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Review
. 2003 May;3(3):331-8.
doi: 10.1586/14737159.3.3.331.

Possible role of matriptase in the diagnosis of ovarian cancer

Michael D Johnson  1 , Michael D Oberst, Chen-Yong Lin, Robert B Dickson
Affiliations
Review

Possible role of matriptase in the diagnosis of ovarian cancer

Michael D Johnson et al. Expert Rev Mol Diagn. 2003 May.

Abstract

There are increasing data that suggest a role for the serine protease matriptase and its inhibitor, hepatocyte growth factor activator inhibitor-1, in the pathogenesis and progression of ovarian cancer. This review will discuss the matriptase/inhibitor system in the context of ovarian cancer and examine the possibility that this system might be a useful therapeutic and/or diagnostic target in this disease.

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