Review
doi: 10.1586/14737159.3.3.331.
Possible role of matriptase in the diagnosis of ovarian cancer
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- PMID: 12779007
- DOI: 10.1586/14737159.3.3.331
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Review
Possible role of matriptase in the diagnosis of ovarian cancer
Expert Rev Mol Diagn.
2003 May.
Abstract
There are increasing data that suggest a role for the serine protease matriptase and its inhibitor, hepatocyte growth factor activator inhibitor-1, in the pathogenesis and progression of ovarian cancer. This review will discuss the matriptase/inhibitor system in the context of ovarian cancer and examine the possibility that this system might be a useful therapeutic and/or diagnostic target in this disease.
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