Autologous stimulation of human lymphocyte subpopulation
- PMID: 127826
- PMCID: PMC2189968
- DOI: 10.1084/jem.142.5.1327
Autologous stimulation of human lymphocyte subpopulation
Abstract
The background stimulation universally seen when lymphocytes are cultured in vitro has been shown to be markedly lowered by reducing the proportion of B lymphocytes. B-rich fractions of lymphocytes had extremely high background stimulation. It is concluded that stimulation of T cells, probably by autologous B cells, provides the most probable explanation for the findings described.
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