Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 May 15;32(5):593-4.
doi: 10.1007/BF01990181.

Is beta-(4-chlorophenyl)-GABA a specific antagonist of substance P on cerebral cortical neurons?

Is beta-(4-chlorophenyl)-GABA a specific antagonist of substance P on cerebral cortical neurons?

J W Phillis. Experientia. .

Abstract

Beta-(4-chlorophenyl)-GABA (Baclofen, Lioresal) antagonized the excitant actions of acetylcholine and substance P to comparable extents. L-glutamate-induced excitation was affected to a lesser extent. These findings do not support the suggestion that beta-(4-chlorophenyl)-GABA is a specific substance P antagonist.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Brain Res. 1975 Oct 24;97(1):177-80 - PubMed
    1. Brain Res. 1974 Apr 26;70(3):501-5 - PubMed
    1. Exp Neurol. 1974 May;43(2):414-23 - PubMed
    1. Brain Res. 1973 May 17;54:376-80 - PubMed
    1. Neurology. 1974 Oct;24(10):957-63 - PubMed