Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003 Jun;53(6):804-7.
doi: 10.1002/ana.10597.

Regular exercise is beneficial to a mouse model of amyotrophic lateral sclerosis

Ilias G Kirkinezos  1 , Dayami Hernandez, Walter G Bradley, Carlos T Moraes
Affiliations

Regular exercise is beneficial to a mouse model of amyotrophic lateral sclerosis

Ilias G Kirkinezos et al. Ann Neurol. 2003 Jun.

Abstract

We tested whether a regular exercise regimen was associated with a change in the life span of G93A-SOD1 transgenic mice, a model of familial ALS. Regular treadmill running for 10 weeks led to a significant increase in the life span of G93A-SOD1 mice. The effect was stronger in male mice, whereas there was only a trend between exercised and sedentary female G93A-SOD1 mice. The data suggest that regular exercise has a beneficial effect on the progression of ALS.

PubMed Disclaimer

Publication types

LinkOut - more resources