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Review
. 2002;23(5-6):499-511.
doi: 10.1023/a:1023414624092.

Stretching and visualizing titin molecules: combining structure, dynamics and mechanics

Miklós S Z Kellermayer  1 , László Grama
Affiliations
Review

Stretching and visualizing titin molecules: combining structure, dynamics and mechanics

Miklós S Z Kellermayer et al. J Muscle Res Cell Motil. 2002.

Abstract

The details of the global and local structure and function of titin, a giant filamentous intrasarcomeric protein are largely undiscovered. Here we discuss a combination of bulk-solution and novel single-molecule techniques that may lend unique insights into titin's molecular dynamic, structural and mechanical characteristics.

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