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. 1976 May;17(5):332-4.
doi: 10.1136/gut.17.5.332.

Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis

M Simon, M Bourel, R Fauchet, B Genetet

Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis

M Simon et al. Gut. 1976 May.

Abstract

The frequency of HLA-A3 and HLA-B14 antigens was significantly higher in a series of 51 patients with idiopathic haemochromatosis than in a control group, being respectively 78-4 versus 27-0% and 25-5 versus 3-4%. This finding strongly supports the suggestion that idiopathic haemochromatosis is a genetic disease and suggests that the gene(s) responsible for the disease may be linked to the histocompatibility genes.

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