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Review
. 2003 Jun;5(7):667-75.
doi: 10.1016/s1286-4579(03)00092-3.

The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans

Judith N Steenbergen  1 , Arturo Casadevall
Affiliations
Free article
Review

The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans

Judith N Steenbergen et al. Microbes Infect. 2003 Jun.
Free article

Abstract

The origin of virulence in environmental fungi that have no requirement for animal hosts in their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with virulence factors for mammalian pathogenesis that also contribute to environmental survival. C. neoformans virulence may originate from selection pressures imposed by environmental predators.

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