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. 2003 Jun;135(6):898-9.
doi: 10.1016/s0002-9394(02)02222-5.

Treatment of choroidal melanoma using photodynamic therapy

Irene A Barbazetto  1 , Thomas C Lee, Indira S Rollins, Stanley Chang, David H Abramson
Affiliations

Treatment of choroidal melanoma using photodynamic therapy

Irene A Barbazetto et al. Am J Ophthalmol. 2003 Jun.

Abstract

Purpose: To InternetAdvance publication at ajo.com Feb 26, 2002. investigate the effect of photodynamic therapy using verteporfin on choroidal melanoma.

Design: Interventional case series.

Method: Four patients with choroidal melanoma who showed recurrence or no response after previous brachytherapy and transpupillary thermotherapy were treated with photodynamic therapy.

Results: One tumor decreased in size and remained stable for 18 months. One tumor had no growth for 11 months. Two melanomas continued to grow, necessitating enucleation.

Conclusions: Of the four eyes that had failed conventional therapies, two would have been salvaged (to date) with photodynamic therapy. However, additional studies are needed to determine if photodynamic therapy can play a role in the management of choroidal melanoma.

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