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Comment
. 2003 Jun;52(6):431-5.

Oral vitamin D3 decreases fracture risk in the elderly

Janelle Guirguis-Blake  1 , Robert L Phillips
Affiliations
  • PMID: 12791218
Comment

Oral vitamin D3 decreases fracture risk in the elderly

Janelle Guirguis-Blake et al. J Fam Pract. 2003 Jun.

Abstract

Vitamin D3 (or its physiologic equivalent, ergocalciferol), administered at a dose of 100,000 IU every 4 months for 5 years, is effective for primary prevention of fractures in the active elderly aged 65 to 85 years. This treatment regimen has no effect on cardiovascular, cancer, or all-cause mortality. Despite a seemingly large dose averaging 800 IU per day, this regimen is a safe, cheap (<$2 per year), and effective therapy for primary prevention of fractures.

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