Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2003 Jun;11(6):608-9.
doi: 10.1016/s0969-2126(03)00102-3.

A pivotal role of the coiled coil of Sir4

Rui-Ming Xu
Free article
Comment

A pivotal role of the coiled coil of Sir4

Rui-Ming Xu. Structure. 2003 Jun.
Free article

Abstract

The C terminus of Sir4 forms a coiled-coil structure. The coiled-coil domain is responsible for the dimerization of Sir4 and contains the binding site of Sir3. Structural and biochemical analyses of the Sir4 coiled-coil domain provide important insights into the molecular mechanisms of Sir3-Sir4 interaction and the assembly of a ternary Sir2/Sir3/Sir4 complex that are essential for epigenetic control of gene expression in S. cerevisiae.

PubMed Disclaimer

Comment on

MeSH terms

Substances

LinkOut - more resources