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Review
. 2003 Jun 15:187 Suppl 2:S327-34.
doi: 10.1086/374758.

Drosophila melanogaster antimicrobial defense

Affiliations
Review

Drosophila melanogaster antimicrobial defense

Charles Hetru et al. J Infect Dis. .

Abstract

The Drosophila melanogaster host defense is complex but remarkably efficient. It is a multifaceted response to a variety of fungal, bacterial, and parasitic invaders. Current knowledge is discussed on recognition of infectious microorganisms and on the activation of intracellular signaling cascades that concur with the expression of numerous immune-responsive genes, among which, to date, the most prominent appear to encode potent antimicrobial peptides.

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