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Case Reports
. 2003 Jun;79(3):179-84.
doi: 10.1136/sti.79.3.179.

Central pontine myelinolysis complicating treatment of multicentric Castleman's disease and Kaposi's sarcoma in a patient with AIDS

A Apoola  1 , J Ross, M J Duddy, V Mudaliar, E L Jones, M Huengsberg, R F Miller
Affiliations
Case Reports

Central pontine myelinolysis complicating treatment of multicentric Castleman's disease and Kaposi's sarcoma in a patient with AIDS

A Apoola et al. Sex Transm Infect. 2003 Jun.

Abstract

An HIV positive black African woman presented with widespread lymphadenopathy and pancytopenia that had been ascribed to tuberculosis. Lymph node biopsy showed both Kaposi's sarcoma and multicentric Castleman's disease. Despite antiretroviral therapy and chemotherapy the patient deteriorated, developing confusion and dysphasia. A cranial magnetic resonance scan showed central pontine myelinolysis. Despite supportive therapy the patient died.

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