Add-on or step-up trials for new drug development in rheumatoid arthritis: a new standard?

Affiliations

Maarten Boers. Arthritis Rheum. 2003 Jun.

. 2003 Jun;48(6):1481-3.

doi: 10.1002/art.11141.

¹ Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands. keb.info@vumc.nl

No abstract available

Comment in

Counterpoint from the trenches: a pragmatic approach to therapeutic trials in rheumatoid arthritis.
Strand V. Strand V. Arthritis Rheum. 2004 Apr;50(4):1344-7. doi: 10.1002/art.20153. Arthritis Rheum. 2004. PMID: 15077319 Review. No abstract available.
Add-on or step-up trials in rheumatoid arthritis: comment on the article by Boers.
Pincus T. Pincus T. Arthritis Rheum. 2004 Apr;50(4):1351; author reply 1351-2. doi: 10.1002/art.20161. Arthritis Rheum. 2004. PMID: 15077322 No abstract available.