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Review
. 2003 Jun 5;38(5):675-7.
doi: 10.1016/s0896-6273(03)00329-5.

Together at last: bHLH and LIM-HD regulators cooperate to specify motor neurons

Douglas W Allan  1 , Stefan Thor
Affiliations
Free article
Review

Together at last: bHLH and LIM-HD regulators cooperate to specify motor neurons

Douglas W Allan et al. Neuron. .
Free article

Abstract

bHLH and LIM-HD transcription factors were originally thought to act at different stages of neurogenesis: bHLHs as neuronal "inducers" and LIM-HDs as postmitotic subtype determinants. These distinctions are becoming blurred, and a current study by Lee and Pfaff in this issue of Neuron shows that interaction between these factors functions to synchronize neurogenesis with neuronal cell type specification.

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