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Clinical Trial
. 1992 Nov;175(5):397-400.

A double-blinded multicenter trial of somatostatin in the treatment of acute pancreatitis

I Gjørup  1 , O Roikjaer, B Andersen, F Burcharth, C Hovendal, S A Pedersen, P Christiansen, P Wara, J C Andersen, I Balslev, et al.
Affiliations
  • PMID: 1279821
Clinical Trial

A double-blinded multicenter trial of somatostatin in the treatment of acute pancreatitis

I Gjørup et al. Surg Gynecol Obstet. 1992 Nov.

Abstract

To evaluate the effect of somatostatin in the treatment of acute pancreatitis, 63 patients were randomly allocated to continuous intravenous infusion for three days of 250 micrograms of somatostatin (Dura Scan, Odense, Denmark) per hour (n = 33), or placebo (n = 30). Patients with a first attack of pancreatitis, serum amylase level of more than 450 units per liter and symptoms for less than 24 hours were eligible for participation in the study. Apart from a slightly significant faster decrease in serum amylase concentrations, we were unable to demonstrate any significant benefit from somatostatin with regard to paraclinical values and clinical course.

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