Structure-function subcompartments of the mammalian cell nucleus as revealed by the electron microscopic affinity cytochemistry
- PMID: 1280186
- DOI: 10.1016/s0309-1651(05)80021-9
Structure-function subcompartments of the mammalian cell nucleus as revealed by the electron microscopic affinity cytochemistry
Abstract
This electron microscopy review documents the in situ cytochemical localization of important nuclear structures and relates this to the important nuclear functions of RNA transcription and processing. With the help of specific probes (antibodies, nucleic acid probes), a comprehensive picture of nuclear subcompartmentalization is beginning to emerge.