doi: 10.1126/science.1085371.
Evolution of the protein repertoire
Affiliations
- PMID: 12805536
- DOI: 10.1126/science.1085371
Item in Clipboard
Evolution of the protein repertoire
Science.
.
Abstract
Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.
Similar articles
-
The generation of new protein functions by the combination of domains.Structure. 2007 Jan;15(1):85-99. doi: 10.1016/j.str.2006.11.009. Structure. 2007. PMID: 17223535
-
Fancy footwork in the sequence space shuffle.Nat Biotechnol. 2006 Mar;24(3):328-30. doi: 10.1038/nbt0306-328. Nat Biotechnol. 2006. PMID: 16525408 No abstract available.
-
The relationship between domain duplication and recombination.J Mol Biol. 2005 Feb 11;346(1):355-65. doi: 10.1016/j.jmb.2004.11.050. Epub 2004 Dec 23. J Mol Biol. 2005. PMID: 15663950
-
Enzyme redesign.Chem Rev. 2001 Oct;101(10):3027-46. doi: 10.1021/cr000049n. Chem Rev. 2001. PMID: 11710061 Review. No abstract available.
-
Emergence of diverse biochemical activities in evolutionarily conserved structural scaffolds of proteins.Curr Opin Chem Biol. 2003 Feb;7(1):12-20. doi: 10.1016/s1367-5931(02)00018-2. Curr Opin Chem Biol. 2003. PMID: 12547421 Review.
Cited by
-
Evolutionarily consistent families in SCOP: sequence, structure and function.BMC Struct Biol. 2012 Oct 18;12:27. doi: 10.1186/1472-6807-12-27. BMC Struct Biol. 2012. PMID: 23078280 Free PMC article.
-
The DPY-30 domain and its flanking sequence mediate the assembly and modulation of flagellar radial spoke complexes.Mol Cell Biol. 2012 Oct;32(19):4012-24. doi: 10.1128/MCB.06602-11. Epub 2012 Jul 30. Mol Cell Biol. 2012. PMID: 22851692 Free PMC article.
-
Complete thermodynamic and kinetic characterization of the isomer-specific interaction between Pin1-WW domain and the amyloid precursor protein cytoplasmic tail phosphorylated at Thr668.Biochemistry. 2012 Oct 30;51(43):8583-96. doi: 10.1021/bi3008214. Epub 2012 Oct 16. Biochemistry. 2012. PMID: 23025283 Free PMC article.
-
Membrane topology and predicted RNA-binding function of the 'early responsive to dehydration (ERD4)' plant protein.PLoS One. 2012;7(3):e32658. doi: 10.1371/journal.pone.0032658. Epub 2012 Mar 14. PLoS One. 2012. PMID: 22431979 Free PMC article.
-
Viral proteins acquired from a host converge to simplified domain architectures.PLoS Comput Biol. 2012 Feb;8(2):e1002364. doi: 10.1371/journal.pcbi.1002364. Epub 2012 Feb 2. PLoS Comput Biol. 2012. PMID: 22319434 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
