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Review
. 1992 Nov;232(5):457-60.
doi: 10.1111/j.1365-2796.1992.tb00615.x.

Amylase-producing IgD-type multiple myeloma

A Delannoy  1 , J Hamels, C Mecucci, P Fally, G Wallef, C de Fooz, B Carlier
Affiliations
Review

Amylase-producing IgD-type multiple myeloma

A Delannoy et al. J Intern Med. 1992 Nov.

Abstract

We describe the case of a 63-year-old woman with an IgD-type multiple myeloma and hyperamylasaemia. The evolution of the amylase concentration, the immunohistochemical data and the intracellular amylase contents of the plasma cell were consistent with secretion of amylase by the malignant clone. Moreover, cytogenetic analysis of the bone marrow revealed two structural rearrangements involving chromosome 1 near the amylase locus. Multiple myeloma should be added to the amylase-secreting tumours. This rare entity is not confined to Japan, where it was first recognized.

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