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Review
. 2003 Jul;89(7):793-800.
doi: 10.1136/heart.89.7.793.

HIV and cardiovascular medicine

B D Prendergast  1
Affiliations
Review

HIV and cardiovascular medicine

B D Prendergast. Heart. 2003 Jul.
No abstract available

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Figures

Figure 1
Figure 1
HIV related cardiomyopathy. (A) The heart is enlarged, principally from ventricular dilatation, and there is mild hypertrophy with diffuse endocardial fibrous thickening. Histological examination (B) may reveal myocyte hypertrophy with increased interstitial collagen or (C) evidence of myocarditis with lymphocytic infiltrate and myocyte necrosis. Reproduced with permission from D’Amati et al. Copyright 2001 New York Academy of Sciences, USA.
Figure 2
Figure 2
Infective endocarditis of the tricuspid valve in an HIV positive drug user with a large polypoid thrombotic lesion attached to the posterior leaflet (arrow). Reproduced with permission from D’Amati et al. Copyright 2001 New York Academy of Sciences, USA.
Figure 3
Figure 3
(A) Cardiac Kaposi’s sarcoma with typical red purple coalescent epicardial plaques. Histological examination reveals spindle cells surrounding slit-like capillary vessels. (B) HIV related large cell B immunoblastic lymphoma involving the interatrial septum. Histological examination demonstrates lymphomatous myocardial infiltration associated with diffuse myocardial damage. Reproduced with permission from D’Amati et al. Copyright 2001 New York Academy of Sciences, USA.
Figure 4
Figure 4
Linear age trends for the underlying cause of 93 HIV related deaths in children. Reproduced with permission from Langston C et al. Human immunodeficiency virus-related mortality in infants and children: data from the pediatric pulmonary and cardiovascular complications of vertically transmitted HIV (P2C2) study. Copyright Pediatrics 2001;107:328–38.
See this image and copyright information in PMC

References

    1. Lewis W. Cardiomyopathy in AIDS: a pathophysiological perspective. Prog Cardiovasc Dis 2000;43:151–70. ▸ A detailed review of the pathogenesis, pathophysiology, and epidemiology of HIV related cardiomyopathy with summaries of recent basic scientific advances and proposed in vivo models. Contains 226 references. - PubMed
    1. Barbaro G, Fisher SD, Pellicelli AM, et al. The expanding role of the cardiologist in the care of HIV infected patients. Heart 2001;86:365–7. ▸ A concise review article summarising the everyday cardiac complications of HIV infection likely to present to the busy practising cardiologist. - PMC - PubMed
    1. Arshad A, Bansal A, Patel RC. Cardiac complications of human immunodeficiency virus infection: diagnostic and therapeutic considerations. Heart Disease 2000;2;133–45. ▸ A more detailed comprehensive review outlining the cardiac complications of HIV infection described to date. Contains 162 references. - PubMed
    1. Yunis NA, Stone VE. Cardiac manifestations of HIV/AIDS: a review of disease spectrum and clinical management. J Acquir Immune Defic Syndr Hum Retrovirol 1998;18:145–54. - PubMed
    1. D’Amati G, Di Gioia CR, Gallo P. Pathological findings of HIV-associated cardiovascular disease. Ann N Y Acad Sci 2001;946;23–45. ▸ A superbly illustrated review focusing on HIV associated cardiovascular pathology, correlating the morphologic findings to clinical syndromes of HIV and AIDS. - PubMed

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