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Review
. 2003 Jun;111(12):1805-12.
doi: 10.1172/JCI18921.

C-reactive protein: a critical update

Mark B Pepys  1 , Gideon M Hirschfield
Affiliations
Review

C-reactive protein: a critical update

Mark B Pepys et al. J Clin Invest. 2003 Jun.

Erratum in

  • J Clin Invest. 2003 Jul;112(2):299
No abstract available

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Figures

Figure 1
Figure 1
Molecular structure and morphology of human CRP. (a) Negatively stained electron micrograph showing the typical pentameric disc-like structure face-on and side-on (arrows). (b) Ribbon diagram of the crystal structure, showing the lectin fold and the two calcium atoms (spheres) in the ligand-binding site of each protomer (6). (c) Space-filling model of the CRP molecule, showing a single phosphocholine molecule located in the ligand-binding site of each protomer (6).
See this image and copyright information in PMC

References

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    1. Hutchinson WL, et al. Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population. Clin. Chem. 2000;46:934–938. - PubMed
    1. Szalai AJ, McCrory MA, Cooper GS, Wu J, Kimberly RP. Association between baseline levels of C-reactive protein (CRP) and a dinucleotide repeat polymorphism in the intron of the CRP gene. Genes Immun. 2002;3:14–19. - PubMed

Publication types