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Review
. 1992 Dec;4(6):733-40.
doi: 10.1016/0952-7915(92)90054-i.

Genetic and immunological mechanisms in the pathogenesis of systemic lupus erythematosus

C G Drake  1 , B L Kotzin
Affiliations
Review

Genetic and immunological mechanisms in the pathogenesis of systemic lupus erythematosus

C G Drake et al. Curr Opin Immunol. 1992 Dec.

Abstract

Recent research in systemic lupus erythematosus and animal models of lupus has provided new insight into the pathogenesis of this complex autoimmune disease. Progress has been made towards understanding the genetic contributions to disease susceptibility and induction, as well as towards elucidation of the lymphocyte abnormalities involved in pathogenic autoantibody production.

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