Review
doi: 10.1301/nr.2003.may.183-186.
Is black cohosh estrogenic?
Affiliations
- PMID: 12822708
- DOI: 10.1301/nr.2003.may.183-186
Item in Clipboard
Review
Is black cohosh estrogenic?
Nutr Rev.
2003 May.
Abstract
Many women seek safe and effective alternative therapies for the treatment of menopausal symptoms. Black cohosh, a botanical product, is one such treatment. Its mechanism of action may involve estrogenic effects, but new data dispute the estrogenic theory and indicate that extracts of black cohosh do not bind to the estrogen receptor, up-regulate estrogen-dependent genes, or stimulate the growth of estrogen-dependent tumors in animal models.
Similar articles
-
Effects of standardized isopropanolic black cohosh and estrogen on salivary function in ovariectomized rats.Biomed Pharmacother. 2018 Jan;97:1438-1444. doi: 10.1016/j.biopha.2017.11.038. Epub 2017 Nov 16. Biomed Pharmacother. 2018. PMID: 29156534
-
Black cohosh, a menopausal remedy, does not have estrogenic activity and does not promote breast cancer cell growth.Int J Oncol. 2003 Nov;23(5):1407-12. doi: 10.3892/ijo.23.5.1407. Int J Oncol. 2003. PMID: 14532983
-
Black cohosh does not exert an estrogenic effect on the breast.Nutr Cancer. 2007;59(2):269-77. doi: 10.1080/01635580701506968. Nutr Cancer. 2007. PMID: 18001221
-
Black cohosh: an alternative therapy for menopause?Nutr Clin Care. 2002 Nov-Dec;5(6):283-9. doi: 10.1046/j.1523-5408.2002.05603.x. Nutr Clin Care. 2002. PMID: 12557811 Review.
-
The non-estrogenic alternative for the treatment of climacteric complaints: Black cohosh (Cimicifuga or Actaea racemosa).J Steroid Biochem Mol Biol. 2014 Jan;139:302-10. doi: 10.1016/j.jsbmb.2013.02.007. Epub 2013 Feb 28. J Steroid Biochem Mol Biol. 2014. PMID: 23459142 Review.
Cited by
-
Does Cimicifuga racemosa have the effects like estrogen on the sublingual gland in ovariectomized rats?Biol Res. 2017 Mar 14;50(1):11. doi: 10.1186/s40659-017-0115-x. Biol Res. 2017. PMID: 28288692 Free PMC article.
-
A comparison of the effects of estrogen and Cimicifuga racemosa on the lacrimal gland and submandibular gland in ovariectomized rats.PLoS One. 2015 Mar 20;10(3):e0121470. doi: 10.1371/journal.pone.0121470. eCollection 2015. PLoS One. 2015. PMID: 25793872 Free PMC article.
-
Botanical modulation of menopausal symptoms: mechanisms of action?Planta Med. 2013 May;79(7):538-53. doi: 10.1055/s-0032-1328187. Epub 2013 Feb 13. Planta Med. 2013. PMID: 23408273 Free PMC article. Review.
-
Management of hot flashes in breast cancer survivors and men with prostate cancer.Curr Oncol Rep. 2004 Jul;6(4):285-90. doi: 10.1007/s11912-004-0037-y. Curr Oncol Rep. 2004. PMID: 15161582 Review.
-
The Phytochemistry of Cherokee Aromatic Medicinal Plants.Medicines (Basel). 2018 Nov 12;5(4):121. doi: 10.3390/medicines5040121. Medicines (Basel). 2018. PMID: 30424560 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
