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. 2003 Mar;55(3):127-31.
doi: 10.1080/1521654031000110208.

The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor

Yan Sun  1 , De-ming Gou, Hui Liu, Xiao Peng, Wen-xin Li
Affiliations
Free article

The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor

Yan Sun et al. IUBMB Life. 2003 Mar.
Free article

Abstract

Nearly one-third of Krupple-type C2H2 zinc finger proteins have a krupple-associated box (KRAB) domain, which may act as a transcriptional repressor. ZNF268, which was novelty isolated from early human embryo, is a typical krupple-type C2H2 zinc finger protein with a conserved KRAB domain. In this report, the KRAB domain of ZNF268 is identified to localize in the nucleus and has transcriptional repressor activity.

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